Python Bindings Packages

pyhmmer

Cython bindings and Python interface to HMMER3.

fastobo

Faultless AST for Open Biomedical Ontologies in Python.

uv-ffi

PyO3 FFI layer for uv's pip_install internals — call uv directly from Python without CLI overhead. Fork of astral-sh/uv v0.10.8.

imgui

Cython-based Python bindings for dear imgui

python-lzo

Python bindings for the LZO data compression library

pyfamsa

Cython bindings and Python interface to FAMSA, an algorithm for ultra-scale multiple sequence alignments.

pyopal

Cython bindings and Python interface to Opal, a SIMD-accelerated database search aligner.

cbapi

Carbon Black API - Python language bindings

geant4-pybind

Alternative python bindings for Geant4 via pybind11

tempo-api-python-client

Python bindings for Tempo - https://apidocs.tempo.io/

comby

Python bindings for Comby

rrdtool

Python bindings for rrdtool

pypublicdecompwt

Python bindings for EUMETSAT's PublicDecompWT

pytantan

Cython bindings and Python interface to Tantan, a fast method for identifying repeats in DNA and protein sequences.

vector-ta

High-performance technical analysis indicators with optional SIMD/CUDA and language bindings.

rhwp-python

PyO3 Python bindings for rhwp — parser and renderer for HWP/HWPX documents (Korean Hancom word processor format)

sfst-transduce

Python bindings for SFST focusing on transducer usage

npdatetime

High-performance Nepali (Bikram Sambat) datetime library based on astronomical calculations. Includes bindings for Python, Django, and JavaScript/WASM.

pyfastani

Cython bindings and Python interface to FastANI, a method for fast whole-genome similarity estimation.

plip

Protein-Ligand Interaction Profiler - Analyze and visualize non-covalent protein-ligand interactions in PDB files according to 📝 Schake, Bolz, et al. (2025), https://doi.org/10.1093/nar/gkaf361

bertini

Bertini 2: The redevelopment of Bertini in C++ and Python.

sciforma

High-performance 3D molecular conformer generation inspired by RDKit's ETKDG algorithm. Built with Rust for maximum speed, providing scientific accuracy and native support for Python, TypeScript (WASM), and CLI.

pyskani

PyO3 bindings and Python interface to skani, a method for fast genomic identity calculation using sparse chaining.

pyfasttext

Yet another Python binding for fastText